Public Health

Botulinum toxin is a biological toxin that has several benefits. It is defined as a neurotoxic protein that is produced by a bacterium. The bacterium species responsible for producing botulinum is known as clostridium botulinum. The toxin is produced for purposes such as medical, cosmetic and research. For proper functioning of the toxin, it is produced in two commercial types botulinum toxin type A and botulinum toxin type B (Pickett). However, the toxin can be dangerous to one’s health whereby an infection of the bacterium results to botulism. This means that the toxin is a lethal toxin that must be used in doses.


Humans have a median lethal dose of 1.3 to 2.1 ng/kg. An excess amount of the toxin affects human body cells resulting to botulism. The toxins degree of biotransformation and rate of elimination is dependent on the amount of the dose ('Botulinum Toxin' 37). A large amount of the toxin is prone to transform and eliminate compared to a small amount. Therefore, botulinum toxin is a toxin that should be used in limited amounts for it to benefit humans.


Dworkin analysis that “Outbreak is Reactive” is a true practical explanation to explain a health outbreak. Health outbreaks are cause by biological, chemical or physical toxins (Haverkos). Therefore, these toxins are highly regenerative and can be produced over and over again over a short period of time. This illustrates why most outbreaks, if not controlled, spread at a very high rate. In addition, the outbreaks can easily be switched and eliminated (Wilson 36). This is because the toxins responsible for the outbreaks depend on variable factors such as temperature that affect their biotransformation or activism. Therefore, Dworkin analysis describes how a practical outbreak occurs.



Works cited


'Botulinum Toxin'. Developmental Medicine & Child Neurology 46 (2004): 36-37. Web.


Haverkos, Harry W. 'Outbreak Investigations Around The World: Case Studies In Infectious Disease Field Epidemiology'. Emerg. Infect. Dis. 15.11 (2009): 1882-1882. Web.


Pickett, Andrew. 'Units, Weights And Concentrations: The Botulinum Toxin Dilemma'. The Botulinum J. 2.1 (2011): 4. Web.


Wilson, Mark L. 'Book Review: Outbreak Investigations Around The World: Case Studies In Infectious Disease Field Epidemiology'. Environ Health Perspect 118.3 (2010): a138-a138. Web.